CBD is no stranger to most of us now. Anybody knows what this is, may it be for medical or recreational use. Not only in what we saw or heard but also even on the internet. Even if you try to search this three-letter word online, in just seconds, the results are overwhelming. Well, that’s a fascinating indication of interest in CBD or cannabidiol. CBD is becoming popular as a new supplement with a promising value on treating different types of conditions. It includes anxiety, insomnia, depression, and pain relief, just to name a few. CBD also comes in various products, from oils, lotions, and edibles. But the real question, does CBD work?
Cannabidiol from Hemp
CBD (cannabidiol) is one of the hundred compounds in hemp or marijuana plants. It usually has only 0.3% THC content, which is another cannabinoid. Individuals confuse CBD with THC or tetrahydrocannabinol, the psychoactive compound of the plant. Contrary to THC, CBD doesn’t cause any euphoric effects or “high.” It doesn’t contain any psychoactive properties and does not affect the same receptors as THC. Both THC and CBD act in the endocannabinoid system in our body. The system plays a role in various processes in the body, including memory, mood, appetite, digestion, and pain sensation.
Most common that many people use is CBD oil. It can offer alternative medications than using prescribed medications. Some of these medications can cause adverse side effects as well as can be addictive. Thus, however, a need for thorough research to clarify the pain-relieving benefits of these CBD products.
Well, go on, continue to scroll your screen, as we walk through on how significant CBD products are, especially as a pain reliever. You can also consult with your doctor if it might be an option for your condition.
CBD Pain Relief for Persistent Pain or Chronic Pain
All of us have what we called an ECS or endocannabinoid in our body, which is a cell-signaling system. It is an endogenous (the substance that is within the body) lipid-based retrograde neurotransmitter (sending signal backward) that is bound to cannabinoid receptors. Some studies have said the CBD interacts with the endocannabinoid receptors in both the brain and the immune system. These receptors are composed of tiny proteins that are attached to the cells. They are responsible for receiving the signal from different stimuli and can help the cells to respond. The response provides pain-relieving and anti-inflammatory effects that can manage the pain. It only means that CBD products like oils can benefit those individuals with chronic pain.
A review in 2018 assessed that CBD could work as a pain-relieving medication. The review took up studies that are conducted between 1975 up to 2018. It examined different kinds of pain, including cancer pain, fibromyalgia, and neuropathic pain. Based on the studies conducted, researchers assume that CBD is an overall effective for pain management. Moreover, it doesn’t cause any side effects rather than other pain-relieving medications.
CBD and Migraine
Migraine can cause moderate to severe pain with throbbing sensation and can last up to 4 hours or even up to 3 days. Even with a slight movement, mundane activities, or being around light and noise can trigger the symptoms.
Some prescribed medications can help the symptoms but temporarily. Also, there are concerned about medications about their adverse effects on the body. Well, this is where CBD takes place. There are only a few research about the use of cannabis for alleviating migraines. The existing research about CBD only looks at the combination with THC.
Moreover, there are no published reviews about the effects of CBD alone for treating migraines. Due to the obstacles in cannabis legalization and regulation on CBD, there is only few research on it.
CBD Pain Relief for Migraine
A study conducted in 2017 in which a group of researchers presented their studies about CBD for migraines. The researchers are from the European Academy of Neurology (EAN). In the first phase of their research, it composes 48 individuals with migraines receive the combination of THC and CBD. One of the compounds has a THC content of about 19%. While the other compound contains 9% of CBD without any THC content on it, both of the compounds were for oral intake. The doses below 100mg had no effects as when the doses increase to 200 mg, and there is a difference in pain reduction up to 55%.
In the second phase of their study, participants that receive both THC and CBD saw an improvement. Their migraine attacks have reduced and fall by 40.4% with a daily dose of 200mg. The combination of THC and CBD was a little bit more effective than other types of medication, such as amitriptyline. Amitriptyline is a tricyclic antidepressant drug that can reduce by 40.1% in participants.
Those people who suffer cluster headaches may also find relief on the combination of two compounds. However, if they only have a history of childhood migraines.
CBD Pain Relief for Joint Inflammation or Arthritis Pain
Arthritis is joint inflammation, but also a term used to describe over hundreds of conditions that can affect the joints. Those with this arthritis may experience swelling on their joints, and its primary symptoms are stiffness. This condition is typically worsening as the age grows. There are two common types of joint inflammation or arthritis, including osteoarthritis and rheumatoid arthritis. Thus, this will affects not only the daily tasks or work of an individual but also its overall well-being.
A study conducted in 2016 in which researchers use CBD on a test by using rats with arthritis. They applied CBD gel on the rats for four days straight with amounts of 0.6, 3.1, 6.2, and 62.3mg per day. They found out that it can reduce the inflammation and pain from the joints of the rats. Moreover, there are no apparent negative side effects shown.
The rats that received small doses of 0.6 to 3.1mg did not improve their pain scores. They found out that if they give a hefty dose of 6.2mg per day can reduce the swelling and pain from the rats. Moreover, those rats that received a dose of 62.3mg per day has a similar outcome to the rats given with 6.2mg of dosage a day. For those reasons, receiving a larger dose doesn’t result in them having less pain.
The pain-relieving and anti-inflammatory properties of CBD have potential benefits for arthritis. However, thorough research and studies are needed to understand its benefits for arthritis fully.
CBD for Cancer
Many individuals diagnosed with cancer also use CBD and CBD products. Research conducted on mice shows that CBD can prevent the growth of cancerous tumors. Howbeit, the majority of studies have examined the role of CBD in humans in managing pain that is related to cancer and its other treatments.
CBD Pain Relief: for Cancer Related Pain
The National Cancer Institute pointed out that CBD is a possible medical option. It is for reducing the side effects of chemotherapy that usually include vomiting, lack of appetite, and pain.
A cancer-related pain study in 2010 subjects received oral sprays with both THC-CBD extracts. The combination of 2 compounds was used for concurrence with opioids. The study shows that extracts are more effective pain reliever rather than using opioids alone. Moreover, a study in 2013 on THC and THC-CBD oral sprays has the same findings. A lot of researchers from the previous studies worked on the study as well. Although, more evidence is still needed for its proper usage.
Types of CBD Products to Consider
There are different types of CBD products that individuals can use to relieve their pain. It can be applied to the skin, inhaled, or taken orally although there are advantages and disadvantages for each and it may include the following:
CBD may come in the form of capsules, liquid, or edibles. It can be absorbed in the digestive tract in the body. The absorption of these products may be slow, and the dosage intake can be tricky due to the delayed effects, recent meals, or unknown effects to the stomach acid.
Capsules can work for daily usage if doses have been established. Many experts discourage the use of CBD edibles. It may include CBD cookies and gummies due to unreliable dosing. Also, they look attractive in the eyes of young ones and doesn’t come with childproof containers. Same with different types of medicines, CBD edibles should be secured or keeping it out from children.
It can also be absorbed into the bloodstreams by the use of tinctures or liquid sprays. It can be applied under the tongue for at least 1 to 2 minutes. Though it may not taste good, yet the effects may be noticeable within 15 to 45 minutes.
CBD Pain Relief: Inhaled
CBD can be inhaled by the use of vape, vaporizer, or pen. However, there is a risk of inhaling chemical byproducts and vapor oils. It is one of the reasons why the CDC (Centers for Disease Control and Prevention) is discouraging to use vape. It is due to extensive hospitalization and even deaths from pulmonary disease.
There are also CBD topical products that include balms, creams, and lotions that can be applied over the pain area. It is still unknown if this product can deliver CBD under the skin. These products may also include over-the-counter ingredients such as camphor, capsaicin, and menthol. For those reasons, it makes it difficult or hard to identify if the positive effects are because of the CBD or from other components.
CBD Pain Relief: Possible Side Effects
As of now, the data given regarding the safety of using CBD are only limited. It is said that CBD does not pose any risk for its users, and most products that came from CBD don’t enter the bloodstreams. The side effects of CBD may include:
- Changes in alertness such as drowsiness
- The decrease in appetite or Diarrhea
- Weight Change
- Agitation and irritability
Some side effects can also happen to individuals without knowing what the cause is. It may include:
- Liver failure
- Injuries resulting from another depressant with alcohol and CBD
CBD may also interact with the following:
- Prescribed medications
- Dietary supplements
- Over-the-counter or OTC drugs
Those who want to use CBD should proceed with caution if their medications contain “grapefruit warning.” Both CBD and grapefruit interfere with the enzymes that can be decisive to drug metabolism.
The same with other drugs, CBD may also increase the risk of having liver toxicity. A study conducted in mice that CBD-rich extracts increased the animals’ liver toxicity.
All in all, CBD is a promising natural remedy for different types of medical conditions and issues. Still, it needs thorough and further studies to understand its benefits for us humans fully. Using CBD products can help you, but it is always best to consult with a proper doctor first as they know all the treatments of your condition.
The information above should not be considered a medical recommendation. The content is written to enrich the reader’s knowledge. Any use of materials and content mentioned in this article should be first consulted about by a physician.